Here’s a quick summary of the challenges of implementing scientific method to test a supposed remedy:
The acid test, however, is in clinical trials, with human beings, and these are complicated. Basically, what you have to do is give a group of people a lot to drink, apply the remedy in question, and then, the next morning, score them on a number of measures in comparison with people who consumed the same amount of alcohol without the remedy. But there are many factors that you have to control for: the sex of the subjects; their general health; their family history; their past experience with alcohol; the type of alcohol you give them; the amount of food and water they consume before, during, and after; and the circumstances under which they drink, among other variables. (Wiese and his colleagues, in their prickly-pear experiment, provided music so that the subjects could dance, as at a party.) Ideally, there should also be a large sample—many subjects.
